Location Discrimination for Mice for Physiological Research Instrumentation

The Spatial Discrimination and Reversal Learning Task is designed for controlled cognitive and physiological research involving spatial memory, reversal learning and hippocampal function. Manufactured by Atico Export with attention to precision, durability and consistent performance for physiological research and experimental laboratory applications.

• Designed to assess spatial memory and reversal learning
• Sensitive to hippocampal dysfunction
• Associated with glutamate receptor regulation and signaling

Task principle :

• Rodents discriminate between two white squares presented on the screen
• Responses to squares on one side are rewarded
• Responses to squares on the other side are followed by a time-out period
• The distance between the two squares varies from trial to trial
• After 7 out of 8 trials are answered correctly, the correct side is reversed to introduce a reversal learning component

Research applications :

• Sensitive to dorsal hippocampal lesions
• Can assess spatial memory and reversal learning
• Performance is affected by the distance between spatial locations

• Spatial memory task with a reversal learning component
• Training paradigms and experimental guidance included
• Flexi-shelf can be used in the rat chamber to improve performance by reducing impulsive responses