Tissue bath systems for Physiological Research Instrumentation

The Tissue Bath System is designed for controlled ex vivo investigation of tissue contractility and vascular reactivity. It provides heated, oxygenated and nutrient-rich perfusate while supporting drug administration and electrical stimulation for pharmacological and physiological studies. Manufactured by Atico Export with quality-focused production and attention to engineering specifications for physiological research, experimental studies and scientific training.

• Designed for contractile measurements in tissues such as aortic, tracheal, iliac and papillary muscles
• Suitable for microvessels such as veins, small arteries and lymph vessels
• Provides heated, oxygenated and nutrient-rich perfusate to tissues
• Supports studies with or without drug administration and electrical stimulation
• Used to investigate the effects of agonists and antagonists on tissue contractility
• Supports dose-response studies for characterization of pharmacological profiles

Research Applications & Use Cases :

• Safety pharmacology
• Heart failure and cardiac model development
• Vascular biology
• Asthma and airway hyperresponsiveness
• Pulmonary fibrosis
• Tobacco and cannabis studies

Techniques & Measurements :

• Isometric tissue contraction
• Tissue contractility measurement
• Dose-response curve generation
• EC50 and Emax calculation

Compatible Software :

• Data acquisition software
• Data reduction software

Configurations :

• Maximum number of baths: 2

• Bath volume: 20 ml

• Bath type: Tubular (PMMA)

• Vessel size: Diameter 500 µm–10 mm; length up to 40 mm

• Independent temperature regulation for each bath

• In-line heating of physiological liquid before entering the bath

• Bath temperature range: 20.0–39.0 °C ± 0.1 °C (68–102.2 °F ± 0.18 °F)

• Hooks: 2 different shapes

• Calibration range: 1 scale, user-defined between 0 and 100 g

• Frame size: 300 × 335 × 206 mm

• Weight: 10 kg

• Bubbling: Frit glass, tube or needle

• Analog output: 0–5 V

• Power supply: 100–240 V

• Transducers: it1, it30

• Positioner resolution: 0.5 mm/rotation (manual)

• Maximum number of baths: 4

• Bath volumes: 5, 10 and 20 ml

• Bath types: Tubular (PMMA), myograph optional

• Same temperature for all baths

• Hooks: 4 different shapes

• Automatic filling

• Automatic emptying

• Calibration range: 3 scales (0–1 / 0–10 / 0–50 g)

• Frame size: 641 × 500 × 345 mm

• Weight: 18 kg

• Bubbling: Frit glass

• Analog output: 0–5 V

• Power supply: 115–230 V

• Transducers: it1, it30

• Positioner resolution: 2.5 µm (0.5 mm/rotation; 200 steps/rotation)

• Modular
• Easy to use
• Reproducible
• Controlled perfusate delivery
• Supports pharmacological and physiological tissue studies