Trial unique Nonmatching-to-Location Task for Mice for Physiological Research Instrumentation

The Trial-Unique Nonmatching-to-Location Task (TUNL) is designed for controlled cognitive and physiological research involving spatial memory, hippocampal function and pattern separation. Manufactured by Atico Export with attention to precision, durability and consistent performance for physiological research and experimental laboratory use.

• Designed to assess spatial memory and hippocampal function
• Sensitive to hippocampal dysfunction and pattern separation

Task principle :

• The subject is presented with a sample location
• Following a delay, the subject is presented with the incorrect sample location (S-) and a correct nonmatching location (S+)
• Uses multiple trial-unique locations to reduce the use of non-spatial mediating strategies

Research applications :

• Sensitive to hippocampal dysfunction
• Can assess the role of the hippocampus in memory and pattern separation
• Performance is affected by the spatial separation between locations

Rat version :

• Uses 15 individual locations

Mouse version :

• Simpler version using 5 positions available